Mixing
Combination chart
Combination data from TripSit (tripsit.me). Their full chart, with explanations, is at combo.tripsit.me. Tap any cell for TripSit's note and sources for that pairing.
From TripSit's chart: "This chart is meant as a quick reference guide and additional research must always be done." Data read 2026-10-24 from TripSit's combos.json (repository); snapshot SHA-256 c655095058771037….
Low Risk & SynergyLow Risk & No SynergyLow Risk & DecreaseCautionUnsafeDangerousNo rating
A colour is not a dose. "Low risk" is TripSit's rating of a pairing, not a statement about any amount, any body, or anything else you have taken. Each substance's page carries the journal-backed interactions and the sources behind them.
| LSD | Mushrooms | DMT | Mescaline | DOx | NBOMes | 2C-x | 2C-T-x | 5-MeO-xxT | Cannabis | Ketamine | MXE | DXM | Nitrous | Amphetamines | MDMA | Cocaine | Caffeine | Alcohol | GHB/GBL | Opioids | Tramadol | Benzodiazepines | MAOIs | SSRIs | AMT | DPH | Lithium | Mephedrone | PCP | Pregabalin | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LSD | |||||||||||||||||||||||||||||||
| Mushrooms | |||||||||||||||||||||||||||||||
| DMT | |||||||||||||||||||||||||||||||
| Mescaline | no rating | ||||||||||||||||||||||||||||||
| DOx | |||||||||||||||||||||||||||||||
| NBOMes | no rating | ||||||||||||||||||||||||||||||
| 2C-x | no rating | no rating | |||||||||||||||||||||||||||||
| 2C-T-x | no rating | no rating | no rating | ||||||||||||||||||||||||||||
| 5-MeO-xxT | no rating | no rating | no rating | ||||||||||||||||||||||||||||
| Cannabis | no rating | no rating | no rating | ||||||||||||||||||||||||||||
| Ketamine | no rating | ||||||||||||||||||||||||||||||
| MXE | no rating | ||||||||||||||||||||||||||||||
| DXM | |||||||||||||||||||||||||||||||
| Nitrous | no rating | no rating | |||||||||||||||||||||||||||||
| Amphetamines | no rating | ||||||||||||||||||||||||||||||
| MDMA | no rating | ||||||||||||||||||||||||||||||
| Cocaine | no rating | ||||||||||||||||||||||||||||||
| Caffeine | no rating | ||||||||||||||||||||||||||||||
| Alcohol | no rating | no rating | no rating | ||||||||||||||||||||||||||||
| GHB/GBL | no rating | ||||||||||||||||||||||||||||||
| Opioids | no rating | ||||||||||||||||||||||||||||||
| Tramadol | |||||||||||||||||||||||||||||||
| Benzodiazepines | no rating | no rating | no rating | ||||||||||||||||||||||||||||
| MAOIs | no rating | no rating | no rating | ||||||||||||||||||||||||||||
| SSRIs | no rating | no rating | |||||||||||||||||||||||||||||
| AMT | no rating | no rating | no rating | no rating | |||||||||||||||||||||||||||
| DPH | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | |||||||||||||||||||||||
| Lithium | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | |||||||||||||||||||
| Mephedrone | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating | |||||||||||||
| PCP | no rating | no rating | no rating | no rating | |||||||||||||||||||||||||||
| Pregabalin | no rating | no rating | no rating | no rating | no rating | no rating | no rating | no rating |
Credit
Combination data from TripSit (tripsit.me). Their full chart, with explanations, is at combo.tripsit.me. Links: https://combo.tripsit.me · https://github.com/TripSit/drugs. No licence is stated for TripSit's drug data; credited to TripSit, and permission asked (outreach/tripsit-permission-request.md).